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WASHINGTON - The combined effects of exercise plus caffeine consumption may be able to ward off skin cancer, U.S. researchers have reported.
The findings were presented at the American Association for Cancer Research Annual Meeting 2012, held in Chicago on March 31- April 4.
The researchers evaluated the effects of caffeine and exercise on mice at high risk for developing skin cancer. Results showed that mice that took a dose of caffeine and exercised with a running wheel experienced 62 percent fewer skin tumors. The volume of tumors also decreased by 85 percent compared with the mice that did not consume caffeine or exercise.
Positive effects were found with either caffeine or exercise alone, but to a lesser extent. Researchers observed a 27 percent reduction in tumors in caffeine-only mice and a 61 percent reduction in tumor size. In the exercise-only mice, researchers found that tumor activity decreased by 35 percent and tumor volume decreased by 70 percent.
"We found that this combination treatment can decrease sunlight-caused skin cancer formation in a mouse model," said Yao-Ping Lu, associate research professor at the Rutgers University. "I believe we may extrapolate these findings to humans and anticipate that we would benefit from these combination treatments as well."?
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